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Stanford's goal: to understand protein folding, protein aggregation, and related diseases.



What are proteins and why do they "fold"? Proteins are biology's workhorses -- its "nanomachines." Before proteins can carry out their biochemical function, they remarkably assemble themselves, or "fold." The process of protein folding, while critical and fundamental to virtually all of biology, remains a mystery. Moreover, perhaps not surprisingly, when proteins do not fold correctly (i.e. "misfold"), there can be serious effects, including many well known diseases, such as Alzheimer's, Mad Cow (BSE), CJD, ALS, and Parkinson's disease.

What does Folding@Home do? Folding@Home is a distributed computing project which studies protein folding, misfolding, aggregation, and related diseases. Stanford uses novel computational methods and large scale distributed computing, to simulate timescales thousands to millions of times longer than previously achieved. This has allowed us to simulate folding for the first time, and to now direct Stanford's approach to examine folding related disease.



How to Join | Project Faqs | Project Add-ons | Statistics | Download Client
New Members
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 Boingo04/17/14 
 DanielGordon04/16/14 
 Huberthans04/15/14 
Off-the-shelf vaccine targeting dendritic cells can safely lead to robust humoral and cellular immunity
Isolating immune cells to study how they ward off oral diseases
Refined categorization may improve prediction of patient survival in RECIST 1.1
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Gene variant makes eaters of processed meat 'more likely to get colorectal cancer'
Teens who conform to gender norms 'more likely to engage in cancer-risk behaviors'
Severe sleep apnea linked to increased risk of stroke, cancer and death
Processing can affect size of nanocarriers for targeted drug delivery
Research shows processing can affect size of nano carriers for targeted drug delivery
Study suggests gene panels as a useful, cheaper alternative to whole-genome sequencing
New blood test 'accurately predicts breast cancer recurrence'
New state-of-the-art educational platform for uro-onco professionals now online
Breakthrough technology to enable doctors to select more effective treatment for cancer patients on a personalised basis
Hepatocellular carcinoma: new advances in diagnosis, staging and treatment all predicted to improve patient outcomes
How and when nerve and brain cells are formed could open doors to targeted cancer therapies
Genetic evidence supports role virus-fighting genes in cancer development
New strategies suggested for kidney regeneration by gene linked to Wilms tumors, a pediatric kidney cancer
ZMYND11 'reads' methylated variant to thwart cancer; tied to breast cancer patient survival
Too much of a protein called c-FLIPR can trigger autoimmune diseases
Tough liver cancer may be treated with immunotherapy
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3D-printed kidneys could become standard for simulated cancer surgery
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Virus-fighting genes linked to mutations in cancer: Genetic evidence supports role of gene family in cancer development
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Neuroscientists explain how memories stick together
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Modified stem cells may offer way to treat Alzheimer's disease
Gene variant gives women higher risk for Alzheimer's
Alzheimer's disease research could be revolutionized by new mouse model
Could Silly Putty help treat neurological disorders?
Researchers at the University of Valencia discover new molecules against Alzheimer's disease
Improving cognition later in life through physical activity
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Why is there an inverse association between cancer and Alzheimer's?
New dementia care models to improve care for older adults with Alzheimer's disease
Working memory boosted by green tea
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Presymptomatic diagnosis of Alzheimer's disease will alter life with a 'brain at risk'
Likely connection between white matter and cognitive health
2 new studies find no evidence of Alzheimer's disease-associated changes in adolescents carrying genetic risk factors
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Study on Mt. Everest shows how people get type 2 diabetes
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New target in flu virus may open route to better drugs
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New agents may revitalize antibiotics to fight superbugs
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Method offers potential for understanding anti-bacterial resistance
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  • Stickies: 0
  • News Articles: 153
  • Pages: 31
New Diagnostic Criteria and Guidelines for Alzheimer
King_N
[H]ard|Folding Administrator


Posts: 98
Points: 2,738,192
Work Units: 6,434

Posted: Mon Apr 25, 2011 04:28 pm
Quote:
Three expert international workgroups convened by the Alzheimers Association and the National Institute on Aging (NIA) have issued the first new criteria and guidelines to diagnose Alzheimers disease in 27 years. The new guidelines update, refine and broaden widely used guidelines published in 1984 by the Alzheimers Association (then known as the Alzheimers Disease and Related Disorders Association) and the National Institute of Neurological and Communicative Disorders and Stroke (now known as the National Institute of Neurological Disorders and Stroke).


Full Article here

Client Version 7(Beta)
King_N
[H]ard|Folding Administrator


Posts: 98
Points: 2,738,192
Work Units: 6,434

Posted: Tue Mar 29, 2011 08:41 pm
Stanford just released a new beta client for version 7.

Quote:
I am happy to announce that after many months of development and testing the new version 7 Folding@home client software is now available for open-beta testing. The V7 client is a complete rewrite of the previous client for Windows, OS-X and Linux with the following goals:

1.To make the installation and startup user-friendly for the novice.
2.To integrate the user interface into a single Monitor/Control program that manages the functionality previously contained in separate clients.
3.To create a forward-looking design that can be readily expanded to incorporate new Folding Cores without the need to issue new client releases.
4.To greatly improve previously problematic aspects including support for SMP, GPU, and the 3D viewer.


Download Available here.
New SMP clients available.
King_N
[H]ard|Folding Administrator


Posts: 98
Points: 2,738,192
Work Units: 6,434

Posted: Mon Feb 28, 2011 07:56 am
Stanford just released the new 6.34 SMP clients.

Download Available here



New Client Released
King_N
[H]ard|Folding Administrator


Posts: 98
Points: 2,738,192
Work Units: 6,434

Posted: Sat Jan 29, 2011 10:44 am
Stanford just released GPU3 client version 641.

Quote:
The changes to this version of the client include the addition of a -forcegpu flag ='nvidia_g80_1.0' ; this flag will signal a compute capability of 1.0 (GPU species=10); if the flag ''nvidia_g80' is used the compute capability will be reported as 1.1 (GPU species=11). Also a pop-up dialog box now appears reporting an error, if the -forcegpu flag is unrecognized; the client then exits.


Download Available here



Everything back to normal
King_N
[H]ard|Folding Administrator


Posts: 98
Points: 2,738,192
Work Units: 6,434

Posted: Fri Dec 31, 2010 03:44 am
Stanford appears to have compleated thier server maintenance, the maintenance they ran did cause a few glitches on this end however everything appears to be back to normal once again.

Have a Happy New Year everyone.
  • Stickies: 0
  • News Articles: 153
  • Pages: 31
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